Population Health Informatics and Disparities Research Lab (PHIDL)

Aize Cao, Ph.D.
Associate Professor
Biomedical Data Science
acao@mmc.edu
The PHIDL is dedicated to addressing health disparities and forecasting patient health outcomes with the desire to enhance overall patient well-being. To achieve this mission, the lab focuses on advancing health informatics and developing machine learning pipelines leveraging multi-modality data to identify patients at risk of adverse health events. Ongoing research involves substance use and mental health disorders, maternal and cardiovascular conditions, and COVID-19. We also seek to identify social determinant of health (SDoH) factors that are associated with undesirable health outcomes.
Dr. Cao has been collaborating with Dr. Lloyda B. Williamson, professor and chair of the Department of Psychiatry and Behavioral Sciences, on research of pregnant or postpartum women with concurrent substance use and mental health disorders. She and Dr. Bishnu Sarker, assistant professor of data science and computer science, are exploring machine learning methods for SDoH identification. Additionally, she has been working with HCA CHARGE consortium on COVID-19 studies.
A complete list of Dr. Cao’s publications is at Google Scholar and more information is available on her personal website.
Grant Support
NSF EIR 2302637, “Excellent in Research: Developing a Knowledge Graph Driven Integrative Framework for Explainable Protein Function Prediction via Generative Deep Learning”
Bishnu Sarker (PI), Aize Cao (Co-PI)
1/8/2023 – 7/31/2026
3U54MD007586-37S1, “Social Determinant of Health Identification from Clinical Charts for Patients with Substance Use Disorder”
Samuel E Adunyah (parent PI), Aize Cao (supplement PI)
1/6/2023 – 5/31/2025
NSF MRI 2117282, “MRI: Acquisition of a High-Performance Computer System to Support Research and Training in Computational Biology and Data Science at Meharry Medical College”
Aize Cao (PI), Qingguo Wang (Co-PI)
10/2021 – 09/2024
Meharry Internal COVID-19 pilot grant, “Developing Risk Predication Models for Patients with Comorbid Substance Use Disorder Before and Among COVID-19”
Amount: $50,000
Aize Cao (PI), Lloyda B. Williamson (co-PI)
9/2021 – 3/2024
Completed Grant Projects
3U54MD007586-35S5, “A retrospective study to examine the correlation between high cholesterol and substance use disorder,” supported pilot study
Amount: $30,000
PI: Aize Cao, Shawn Goodwin, 4/2022 – 5/2023
Lab Members
Clarence White
M.S. Data Science
School of Applied Computational Sciences
Supported by RCMI internal pilot study
Noah Whittenbarger
M.S. Biomedical Data Science
School of Applied Computational Sciences
NIH R25 Scholar
Jonathan Low
School of Medicine
Supported by internal COVID-19 grant
Remi Parker
School of Medicine
Supported by internal COVID-19 grant
Collaborators
Internal
Lloyda B. Williamson, M.D.
Professor and Chair
Department of Psychiatry and Behavioral Sciences
Samuel E. Adunyah, Ph.D.
Chair and Professor
Biochemistry and Cancer Biology
School of Medicine
J. Shawn Goodwin, Ph.D.
Associate Professor
Biochemistry and Cancer Biology
School of Medicine
External
Russell E. Poland, Ph.D.
AVP for Research, Extramural and Collaborative Partnerships at HCA Healthcare
President/Chief Research Officer at HCA PACE
Sr Lecturer at Harvard Medical School